AustralieFrV1, Main, Exploration, bibRecord, 006807

Pregnancy Promotes Melanoma Metastasis through Enhanced Lymphangiogenesis

Identifieur interne : 006807 ( Main/Exploration ); précédent : 006806; suivant : 006808

Pregnancy Promotes Melanoma Metastasis through Enhanced Lymphangiogenesis

Auteurs : Kiarash Khosrotehrani [France, Australie] ; SAU NGUYEN HUU [France] ; Aurélie Prignon [France] ; Marie-Françoise Avril [France] ; Françoise Boitier [France] ; Michèle Oster [France] ; Laurent Mortier [France] ; Marie-Aleth Richard [France] ; Eve Maubec [France] ; Delphine Kerob [France] ; Sandrine Mansard [France] ; Charbel Merheb [France] ; Philippe Moguelet [France] ; Dany Nassar [France] ; Sarah Guegan [France] ; Selim Aractingi [France]

Source :

The American journal of pathology [ 0002-9440 ] ; 2011.

RBID : Pascal:11-0197587

Descripteurs français

Pascal (Inist)
- Mélanome malin, Gestation, Femelle, Métastase, Anatomopathologie, Lymphangiogenèse.

English descriptors

KwdEn :
- Anatomic pathology, Female, Lymphangiogenesis, Malignant melanoma, Metastasis, Pregnancy.

Abstract

The relationships of pregnancy and melanoma have been debatable. Our aim was to assess the influence of gestation on the course of melanoma in a classic murine model of tumor progression and in women. B16 mouse melanoma cells were injected in nonpregnant or pregnant mice on day 5 of gestation. Animals were evaluated for tumor progression, metastases, and survival. Tumor sections were analyzed for lymphatic and blood vessel number and relative surface and expression of angiogenic growth factors. Finally, primary melanomas from pregnant and nonpregnant women, matched for age and tumor thickness, were also considered. Tumor growth, metastasis, and mortality were increased in B16-injected pregnant mice. Tumors displayed an increase in intratumoral lymph-angiogenesis during gestation. This increased lymphatic angiogenesis was not observed in normal skin during gestation, showing its specificity to the tumor. An analysis of melanoma from pregnant and matched nonpregnant women showed a similar increase in lymphatic vessels. Tumors from pregnant mice had increased expression of vascular endothelial growth factor A at the RNA and protein levels. The increased vascular endothelial growth factor A production by melanoma cells could be reproduced in culture using pregnant mouse serum. In conclusion, pregnancy results in increased lymphangiogenesis and subsequent metastasis. Caution should be applied in the management of patients with advanced-stage melanoma during gestation.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3078435

Affiliations:

Le document en format XML

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<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>INSERM UMR_S938, Centre de Recherche Stint Antoine</s1>
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<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Departments of Dermatology, Assistance Publique Hôpitaux de Paris, Hôpital Tenon</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="1"><inist:fA14 i1="06"><s1>Experimental Dermatology Group, University of Queensland Centre for Clinical Research</s1>
<s2>Brisbane</s2>
<s3>AUS</s3>
<sZ>1 aut.</sZ>
</inist:fA14>
<country>Australie</country>
<wicri:noRegion>Brisbane</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Sau Nguyen Huu" sort="Sau Nguyen Huu" uniqKey="Sau Nguyen Huu" last="Sau Nguyen Huu">SAU NGUYEN HUU</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Université Pierre et Marie Curie, University Paris 06</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>INSERM UMR_S938, Centre de Recherche Stint Antoine</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Prignon, Aurelie" sort="Prignon, Aurelie" uniqKey="Prignon A" first="Aurélie" last="Prignon">Aurélie Prignon</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Université Pierre et Marie Curie, University Paris 06</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>INSERM UMR_S938, Centre de Recherche Stint Antoine</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Avril, Marie Francoise" sort="Avril, Marie Francoise" uniqKey="Avril M" first="Marie-Françoise" last="Avril">Marie-Françoise Avril</name>
<affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Dermatology, Assistance Publique Hôpitaux de Paris, Hôpital Tarnier</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Boitier, Francoise" sort="Boitier, Francoise" uniqKey="Boitier F" first="Françoise" last="Boitier">Françoise Boitier</name>
<affiliation wicri:level="3"><inist:fA14 i1="07"><s1>Department of Dermatology, Assistance Publique Hôpitaux de Paris, Hôpital Tarnier</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>4 aut.</sZ>
<sZ>5 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Oster, Michele" sort="Oster, Michele" uniqKey="Oster M" first="Michèle" last="Oster">Michèle Oster</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Université Pierre et Marie Curie, University Paris 06</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>INSERM UMR_S938, Centre de Recherche Stint Antoine</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mortier, Laurent" sort="Mortier, Laurent" uniqKey="Mortier L" first="Laurent" last="Mortier">Laurent Mortier</name>
<affiliation wicri:level="3"><inist:fA14 i1="08"><s1>Department of DermatologyCHRU Lille, Hôpital Claude Huriez</s1>
<s2>Lille</s2>
<s3>FRA</s3>
<sZ>7 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Hauts-de-France</region>
<region type="old region">Nord-Pas-de-Calais</region>
<settlement type="city">Lille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Richard, Marie Aleth" sort="Richard, Marie Aleth" uniqKey="Richard M" first="Marie-Aleth" last="Richard">Marie-Aleth Richard</name>
<affiliation wicri:level="3"><inist:fA14 i1="09"><s1>Department of Dermatology, Assistance Publique-Hôpitaux de Marseille, CHU Sainte-Marguerite</s1>
<s2>Marseille</s2>
<s3>FRA</s3>
<sZ>8 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Provence-Alpes-Côte d'Azur</region>
<region type="old region">Provence-Alpes-Côte d'Azur</region>
<settlement type="city">Marseille</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Maubec, Eve" sort="Maubec, Eve" uniqKey="Maubec E" first="Eve" last="Maubec">Eve Maubec</name>
<affiliation wicri:level="3"><inist:fA14 i1="10"><s1>Department of Dermatology, Assistance Publique Hôpitaux de Paris, Hôpital Bichat</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>9 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Kerob, Delphine" sort="Kerob, Delphine" uniqKey="Kerob D" first="Delphine" last="Kerob">Delphine Kerob</name>
<affiliation wicri:level="3"><inist:fA14 i1="11"><s1>Department of Dermatology, Assistance Publique Hôpitaux de Paris, Hôpital Saint-Louis</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>10 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Mansard, Sandrine" sort="Mansard, Sandrine" uniqKey="Mansard S" first="Sandrine" last="Mansard">Sandrine Mansard</name>
<affiliation wicri:level="3"><inist:fA14 i1="12"><s1>Department of Dernzatology, Université d'Auvergne Clermont-Ferrand 1, CHU Hôtel-Dieu</s1>
<s2>Clermont-Ferrand</s2>
<s3>FRA</s3>
<sZ>11 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Auvergne-Rhône-Alpes</region>
<region type="old region">Auvergne (région administrative)</region>
<settlement type="city">Clermont-Ferrand</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Merheb, Charbel" sort="Merheb, Charbel" uniqKey="Merheb C" first="Charbel" last="Merheb">Charbel Merheb</name>
<affiliation wicri:level="3"><inist:fA14 i1="04"><s1>Department of Nuclear Medicine, Assistance Publique Hôpitaux de Paris, Hôpital Tenon</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>12 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Moguelet, Philippe" sort="Moguelet, Philippe" uniqKey="Moguelet P" first="Philippe" last="Moguelet">Philippe Moguelet</name>
<affiliation wicri:level="3"><inist:fA14 i1="05"><s1>Department of Pathology, Assistance Publique Hôpitaux de Paris, Hôpital Tenon</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>13 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Nassar, Dany" sort="Nassar, Dany" uniqKey="Nassar D" first="Dany" last="Nassar">Dany Nassar</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Université Pierre et Marie Curie, University Paris 06</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
</affiliation>
</author>
<author><name sortKey="Guegan, Sarah" sort="Guegan, Sarah" uniqKey="Guegan S" first="Sarah" last="Guegan">Sarah Guegan</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Université Pierre et Marie Curie, University Paris 06</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>INSERM UMR_S938, Centre de Recherche Stint Antoine</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Departments of Dermatology, Assistance Publique Hôpitaux de Paris, Hôpital Tenon</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
<author><name sortKey="Aractingi, Selim" sort="Aractingi, Selim" uniqKey="Aractingi S" first="Selim" last="Aractingi">Selim Aractingi</name>
<affiliation wicri:level="4"><inist:fA14 i1="01"><s1>Université Pierre et Marie Curie, University Paris 06</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>14 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
<settlement type="city">Paris</settlement>
</placeName>
<orgName type="university">Université Pierre-et-Marie-Curie</orgName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="02"><s1>INSERM UMR_S938, Centre de Recherche Stint Antoine</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>2 aut.</sZ>
<sZ>3 aut.</sZ>
<sZ>6 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
<affiliation wicri:level="3"><inist:fA14 i1="03"><s1>Departments of Dermatology, Assistance Publique Hôpitaux de Paris, Hôpital Tenon</s1>
<s2>Paris</s2>
<s3>FRA</s3>
<sZ>1 aut.</sZ>
<sZ>15 aut.</sZ>
<sZ>16 aut.</sZ>
</inist:fA14>
<country>France</country>
<placeName><region type="region">Île-de-France</region>
<region type="old region">Île-de-France</region>
<settlement type="city">Paris</settlement>
</placeName>
</affiliation>
</author>
</analytic>
<series><title level="j" type="main">The American journal of pathology</title>
<title level="j" type="abbreviated">Am. j. pathol.</title>
<idno type="ISSN">0002-9440</idno>
<imprint><date when="2011">2011</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
<seriesStmt><title level="j" type="main">The American journal of pathology</title>
<title level="j" type="abbreviated">Am. j. pathol.</title>
<idno type="ISSN">0002-9440</idno>
</seriesStmt>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Anatomic pathology</term>
<term>Female</term>
<term>Lymphangiogenesis</term>
<term>Malignant melanoma</term>
<term>Metastasis</term>
<term>Pregnancy</term>
</keywords>
<keywords scheme="Pascal" xml:lang="fr"><term>Mélanome malin</term>
<term>Gestation</term>
<term>Femelle</term>
<term>Métastase</term>
<term>Anatomopathologie</term>
<term>Lymphangiogenèse</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">The relationships of pregnancy and melanoma have been debatable. Our aim was to assess the influence of gestation on the course of melanoma in a classic murine model of tumor progression and in women. B16 mouse melanoma cells were injected in nonpregnant or pregnant mice on day 5 of gestation. Animals were evaluated for tumor progression, metastases, and survival. Tumor sections were analyzed for lymphatic and blood vessel number and relative surface and expression of angiogenic growth factors. Finally, primary melanomas from pregnant and nonpregnant women, matched for age and tumor thickness, were also considered. Tumor growth, metastasis, and mortality were increased in B16-injected pregnant mice. Tumors displayed an increase in intratumoral lymph-angiogenesis during gestation. This increased lymphatic angiogenesis was not observed in normal skin during gestation, showing its specificity to the tumor. An analysis of melanoma from pregnant and matched nonpregnant women showed a similar increase in lymphatic vessels. Tumors from pregnant mice had increased expression of vascular endothelial growth factor A at the RNA and protein levels. The increased vascular endothelial growth factor A production by melanoma cells could be reproduced in culture using pregnant mouse serum. In conclusion, pregnancy results in increased lymphangiogenesis and subsequent metastasis. Caution should be applied in the management of patients with advanced-stage melanoma during gestation.</div>
</front>
</TEI>
<affiliations><list><country><li>Australie</li>
<li>France</li>
</country>
<region><li>Auvergne (région administrative)</li>
<li>Auvergne-Rhône-Alpes</li>
<li>Hauts-de-France</li>
<li>Nord-Pas-de-Calais</li>
<li>Provence-Alpes-Côte d'Azur</li>
<li>Île-de-France</li>
</region>
<settlement><li>Clermont-Ferrand</li>
<li>Lille</li>
<li>Marseille</li>
<li>Paris</li>
</settlement>
<orgName><li>Université Pierre-et-Marie-Curie</li>
</orgName>
</list>
<tree><country name="France"><region name="Île-de-France"><name sortKey="Khosrotehrani, Kiarash" sort="Khosrotehrani, Kiarash" uniqKey="Khosrotehrani K" first="Kiarash" last="Khosrotehrani">Kiarash Khosrotehrani</name>
</region>
<name sortKey="Aractingi, Selim" sort="Aractingi, Selim" uniqKey="Aractingi S" first="Selim" last="Aractingi">Selim Aractingi</name>
<name sortKey="Aractingi, Selim" sort="Aractingi, Selim" uniqKey="Aractingi S" first="Selim" last="Aractingi">Selim Aractingi</name>
<name sortKey="Aractingi, Selim" sort="Aractingi, Selim" uniqKey="Aractingi S" first="Selim" last="Aractingi">Selim Aractingi</name>
<name sortKey="Avril, Marie Francoise" sort="Avril, Marie Francoise" uniqKey="Avril M" first="Marie-Françoise" last="Avril">Marie-Françoise Avril</name>
<name sortKey="Boitier, Francoise" sort="Boitier, Francoise" uniqKey="Boitier F" first="Françoise" last="Boitier">Françoise Boitier</name>
<name sortKey="Guegan, Sarah" sort="Guegan, Sarah" uniqKey="Guegan S" first="Sarah" last="Guegan">Sarah Guegan</name>
<name sortKey="Guegan, Sarah" sort="Guegan, Sarah" uniqKey="Guegan S" first="Sarah" last="Guegan">Sarah Guegan</name>
<name sortKey="Guegan, Sarah" sort="Guegan, Sarah" uniqKey="Guegan S" first="Sarah" last="Guegan">Sarah Guegan</name>
<name sortKey="Kerob, Delphine" sort="Kerob, Delphine" uniqKey="Kerob D" first="Delphine" last="Kerob">Delphine Kerob</name>
<name sortKey="Khosrotehrani, Kiarash" sort="Khosrotehrani, Kiarash" uniqKey="Khosrotehrani K" first="Kiarash" last="Khosrotehrani">Kiarash Khosrotehrani</name>
<name sortKey="Khosrotehrani, Kiarash" sort="Khosrotehrani, Kiarash" uniqKey="Khosrotehrani K" first="Kiarash" last="Khosrotehrani">Kiarash Khosrotehrani</name>
<name sortKey="Mansard, Sandrine" sort="Mansard, Sandrine" uniqKey="Mansard S" first="Sandrine" last="Mansard">Sandrine Mansard</name>
<name sortKey="Maubec, Eve" sort="Maubec, Eve" uniqKey="Maubec E" first="Eve" last="Maubec">Eve Maubec</name>
<name sortKey="Merheb, Charbel" sort="Merheb, Charbel" uniqKey="Merheb C" first="Charbel" last="Merheb">Charbel Merheb</name>
<name sortKey="Moguelet, Philippe" sort="Moguelet, Philippe" uniqKey="Moguelet P" first="Philippe" last="Moguelet">Philippe Moguelet</name>
<name sortKey="Mortier, Laurent" sort="Mortier, Laurent" uniqKey="Mortier L" first="Laurent" last="Mortier">Laurent Mortier</name>
<name sortKey="Nassar, Dany" sort="Nassar, Dany" uniqKey="Nassar D" first="Dany" last="Nassar">Dany Nassar</name>
<name sortKey="Oster, Michele" sort="Oster, Michele" uniqKey="Oster M" first="Michèle" last="Oster">Michèle Oster</name>
<name sortKey="Oster, Michele" sort="Oster, Michele" uniqKey="Oster M" first="Michèle" last="Oster">Michèle Oster</name>
<name sortKey="Prignon, Aurelie" sort="Prignon, Aurelie" uniqKey="Prignon A" first="Aurélie" last="Prignon">Aurélie Prignon</name>
<name sortKey="Prignon, Aurelie" sort="Prignon, Aurelie" uniqKey="Prignon A" first="Aurélie" last="Prignon">Aurélie Prignon</name>
<name sortKey="Richard, Marie Aleth" sort="Richard, Marie Aleth" uniqKey="Richard M" first="Marie-Aleth" last="Richard">Marie-Aleth Richard</name>
<name sortKey="Sau Nguyen Huu" sort="Sau Nguyen Huu" uniqKey="Sau Nguyen Huu" last="Sau Nguyen Huu">SAU NGUYEN HUU</name>
<name sortKey="Sau Nguyen Huu" sort="Sau Nguyen Huu" uniqKey="Sau Nguyen Huu" last="Sau Nguyen Huu">SAU NGUYEN HUU</name>
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<country name="Australie"><noRegion><name sortKey="Khosrotehrani, Kiarash" sort="Khosrotehrani, Kiarash" uniqKey="Khosrotehrani K" first="Kiarash" last="Khosrotehrani">Kiarash Khosrotehrani</name>
</noRegion>
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</record>

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HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 006807 | SxmlIndent | more

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{{Explor lien
   |wiki=    Wicri/Asie
   |area=    AustralieFrV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     Pascal:11-0197587
   |texte=   Pregnancy Promotes Melanoma Metastasis through Enhanced Lymphangiogenesis
}}

This area was generated with Dilib version V0.6.33.
Data generation: Tue Dec 5 10:43:12 2017. Site generation: Tue Mar 5 14:07:20 2024

Serveur d'exploration sur les relations entre la France et l'Australie

Pregnancy Promotes Melanoma Metastasis through Enhanced Lymphangiogenesis

Pregnancy Promotes Melanoma Metastasis through Enhanced Lymphangiogenesis

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Abstract

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	Serveur d'exploration sur les relations entre la France et l'Australie
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